Yet Another Paper On The Effect Of The Environment On The Body

Yet Another Paper On The Effect Of The Environment On The Body

Yet another paper on the effect of the environment on the body and evidence that our environment can innfluence the next generation via non-genetic mechanisms.

The epigenetic evidence is mounting!

Summary

Physical exercise in combination with cognitive training is known to enhance synaptic plasticity, learning, and memory and lower the risk for various complex diseases including Alzheimer’s disease. Here, we show that exposure of adult male mice to an environmental enrichment paradigm leads to enhancement of synaptic plasticity and cognition also in the next generation. We show that this effect is mediated through sperm RNA and especially miRs 212/132. In conclusion, our study reports intergenerational inheritance of an acquired cognitive benefit and points to specific miRs as candidates mechanistically involved in this type of transmission.

Yet Another Paper On The Effect Of The Environment On The Body Yet Another Paper On The Effect Of The Environment On The Body

 

RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment 

Eva Benito, Cemil Kerimoglu, Binu Ramachandran, Tonatiuh Pena-Centeno, Gaurav Jain, Roman Manuel Stilling, Md Rezaul Islam, Vincenzo Capece, Qihui Zhou, Dieter Edbauer, Camin Dean, André Fischer

Cell Reports 

Volume 23, Issue 2, Pages 546-554 (April 2018)

DOI: 10.1016/j.celrep.2018.03.059 Yet Another Paper On The Effect Of The Environment On The Body

Yet Another Paper On The Effect Of The Environment On The Body
Yet Another Paper On The Effect Of The Environment On The Body
Yet Another Paper On The Effect Of The Environment On The Body
Yet Another Paper On The Effect Of The Environment On The Body

Yet Another Paper On The Effect Of The Environment On The Body

Yet Another Paper On The Effect Of The Environment On The Body

About admin

No Comments

Be the first to start a conversation

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.